Nineteen of the Russian's 21 championships have been achieved on hard courts
A comeback Medvedev won his maiden title for over two years with success over Corentin Moutet in the Almaty Open championship match.
The Russian, a ex- world number one, has had a torrid season, winning just one match at the major tournaments and undergoing a difficult moment at the American major.
The player's unpredictability on the ATP Tour - and difficulties with his serving in specific - led to him dropping out of the top ten and eventually parting ways with long-term mentor Gilles Cervara.
Now working with Thomas Johansson and Rohan Goetzke, Medvedev has gradually improved in the recent weeks - peaking in a tightly fought three-set win over opponent Moutet.
This represents Medvedev's maiden trophy after the Rome competition and first on a hard court since that period of that year.
The win also indicates he has secured twenty-one victories at 21 different competitions.
"It's the first time I have attended a event with my two daughters together, so to secure a title is particularly special," commented tennis professional Daniil Medvedev.
"This title is in tribute of my second daughter her name, because the first title I achieved when my older daughter my daughter was born was for her."
Medvedev, the former major winner, had been defeated in his previous six title deciders, including in the German tournament earlier this year.
Medvedev's defensive approach and frequent outbursts on court had caused commentators to doubt if his capacity to play at the highest level was concluded.
But the player has made changes in the past month, making an effort to approach the net and play assertively, reinforced by an better serving game.
Medvedev came back from a disadvantage in the first set against the challenging opponent, taking 4 of the last five exchanges to go ahead.
Both players exchanged breaks in the second set before Moutet, attempting for his initial ATP Tour victory, gained dominance to force a final set.
He rescued four early-game chances in a tight third set before the Russian won the break to 15 to close out the victory.
Fittingly, the winner earned the win with a point at the front of the court, with the Frenchman failing to manage a volley after over two and a half hours.